150. "It Might Cause a Little Weight Gain": What Her Neurologist Didn't Tell Her About Depakote

"Don't call my doctor." A woman said that to me on a recent call, half joking.

She has head pain every day. She was taking 15 to 20 sumatriptan a month, and Excedrin on the other days. Her insurance covers nine. Nine is the number she gave her doctor.

Her neurologist told her she was in rebound and to stop cold turkey. She tapered carefully instead, and the migraines came right back, exactly the same.

When she went back on her medication, she was scolded and handed a prescription for Depakote.

The only side effect she was told about was a little weight gain. So what is actually on the Depakote label? And why did the real number she finally told me turn out to be good news for her?

In this episode, I cover:

  • How to tell if you're in rebound (medication overuse headache), and why it happens
  • The migraine medication ladder, and how to find the rung you're on
  • Why Depakote is in the top tier of the guidelines, yet is usually prescribed as a last resort
  • What's in Depakote's black box warning, and the everyday side effects reported in the studies
  • Why her elevated liver enzymes mattered, and how Depakote adds to the load your liver has to clear
  • Why scolding someone about her medication doesn't make her take less. It makes her stop telling you.

If you've climbed to the top of the medication ladder, you are not out of options. There is a way back down, one rung at a time.

Please don't make any medication changes based on this episode. Talk with your prescribing doctor first.

Mentioned in this episode:

Episode 19: Why Does Every Medication I Try Stop Working Eventually

Episode 37: Help! I'm In Rebound

Episode 144: I Have Failed You - What A Neurologist Said That Changed Everything

Episode 146: They Told Her Migraines Would Stop At Menopause. They Were Wrong

Related episodes:

Episode 26: Why Do Medications Cause Side Effects?

Episode 136: The Truth About Rebound Headaches and Medication Cycling For Your Migraines 

Episode 142: Why Your Migraines Return When You Stop Medication, and What to Do Next

Listen on Apple Podcasts: https://podcasts.apple.com/us/podcast/healing-migraines-naturally/id1605963584

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